2-Cyano-4-methylpyridine → 2-(2-Furoyl)-4-methylpyridine

Beteiligte Stoffe

Reaktionsschritte

2-Cyano-4-methylpyridine is reacted in an inert atmosphere with an ethereal solution of freshly prepared 2-furoyl-lithium followed by acid hydrolysis to form 2-(2-furoyl)-4-methylpyridine which is then reacted with methyl iodide to form 2-(2-furoyl)-1,4-dimethylpyridinium iodide. Both furoyl compounds exhibit thermal and chemical analgesic properties.

Herkunft & Nachweise