Benzenemethanol, 4-amino-alpha-(aminomethyl)-3,5-dichloro- → 5-[4-[2-[(4-Amino-3,5-dichloro-beta-hydroxyphenethyl)amino]propyl]benzyl]thiazolidine-2,4-dione

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Reaction Steps

5-[4-[2-[(4-Amino-3,5-dichloro-β-hydroxyphenethyl)amino]propyl]benzyl]thiazolidine-2,4-dione was prepared as a 46:54 mixture of diastereoisomers, mp. 195°-201° C., from 2-(4-amino-3,5-dichlorophenyl)-2-hydroxy ethylamine and 5-(4-acetonylbenzyl)thiazolidine-2,4-dione in an analogous manner to that described in Example 5

Provenance & Evidence