Sodium borohydride → 2-Methoxycarbonyl-3-methoxycarbonylmethyl-2-(cis-2-pentenyl)-cyclopentanol

Participants

Reaction Steps

A 220 mg quantity of 5-methoxycarbonyl-4-methoxycarbonylmethyl-5-(cis-2-pentenyl)-2-cyclopentenone (compound (2-b)) and 60 mg of sodium borohydride are dissolved in 50 ml of methanol, and the solution is refluxed for one hour. The same procedure as in Example 1 is thereafter repeated, affording 2-methoxycarbonyl-3-methoxycarbonylmethyl-2-(cis-2-pentenyl)-cyclopentanol (compound (1-b), R1 =R2 =CH3) in a yield of 94.7%, b.p. 74°-78° C./0.01 mm Hg.

Provenance & Evidence