HCID 54458393, compound → HCID 11777635, compound

Participants

Reaction Steps

A solution of 1.75 g methyl 7-hydroxy-5-[2-(3-pyridyl)ethenyl]-hept-2-enoate in 50 ml ethanol is hydrogenated with 0.35 g 10% palladium on charcoal at 3 atmospheres (=3.04 bar) pressure of hydrogen and room temperature for 21 h. The catalyst is filtered off and washed with ethanol (4×10 ml). The filtrate is evaporated to give a yellow oil which is chromatographed to yield methyl 7-hydroxy-5-[2-(3-pyridyl)ethyl]-heptanoate.

Provenance & Evidence