N-[2,6-bis(1-Methylethyl)phenyl]-2-[(1,1-dimethyl-2-phenylethyl)amino]acetamide → 2-[Acetyl[[4-(dimethylamino)phenyl]methyl]amino]-N-[2,6-bis(1-methylethyl)phenyl]acetamide

HRID 465656Notes

Reaction equation

HRID 465656 reaction equation
[CH3:1][CH:2]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH:10]([CH3:12])[CH3:11])[C:5]=1[NH:13][C:14](=[O:27])[CH2:15][NH:16][CH2:17][C:18]1[CH:23]=[CH:22][C:21]([N:24]([CH3:26])[CH3:25])=[CH:20][CH:19]=1)[CH3:3].CC(C1C=CC=C(C(C)C)C=1N[C:41](=[O:54])[CH2:42]NC(C)(C)CC1C=CC=CC=1)C>>[C:41]([N:16]([CH2:17][C:18]1[CH:23]=[CH:22][C:21]([N:24]([CH3:25])[CH3:26])=[CH:20][CH:19]=1)[CH2:15][C:14]([NH:13][C:5]1[C:6]([CH:10]([CH3:11])[CH3:12])=[CH:7][CH:8]=[CH:9][C:4]=1[CH:2]([CH3:1])[CH3:3])=[O:27])(=[O:54])[CH3:42]

Participants

3

Reactant 2

HCID 19874910N-[2,6-bis(1-Methylethyl)phenyl]-2-[(1,1-dimethyl-2-phenylethyl)amino]acetamideHCID 19874958N-[2,6-bis(1-Methylethyl)phenyl]-2-[[[4-(dimethylamino)phenyl]methyl]amino]acetamide

Product 1

HCID 198749422-[Acetyl[[4-(dimethylamino)phenyl]methyl]amino]-N-[2,6-bis(1-methylethyl)phenyl]acetamide

Procedure

When in the procedure of Example 79 an appropriate amount of the product from Example 73 was substituted for the product of Example 5 the title compound was obtained. Total yield, 0.41 g (73%).

Sources & evidence

ORD record
ord-b923193acba640bf86c74b459e0f7375
Source dataset
uspto-grants-1992_10
Patent number
US05153226

Reaction notes

Loading…