Azetidine → HCID 178508572, compound

Participants

Reaction Conditions

Reaction Steps

2-Amino-6-chloropurine (Sigma, lot #69F4064, 1.0 g, 5.8 mmol) was suspended in 50mL acetonitrile. Azetidine (Aldrich, lot #05606HV, 1.0 g, 17.5 mmol) was added and the reaction stirred at 62° C. for 24 hours. The solvents were evaporated to give a white solid which was recrystallized from methanol to yield 0.71 g (3.7 mmol, 65%); mp=280° C.

Provenance & Evidence