HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 46578Generated: October 27, 2026
Sodium Bicarbonate → beta-(N-chloroacetyl-2,6-dimethylphenylamino)propionaldehyde O-methyloxime
https://huagongshe.com/reaction/46578
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | O-Methylhydroxylamine hydrochloride | HCID 521874 | — |
| Reactant | beta-(N-chloroacetyl-2,6-dimethylphenylamino)propionaldehyde | HCID 20543839 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | beta-(N-chloroacetyl-2,6-dimethylphenylamino)propionaldehyde O-methyloxime | HCID 53798477 | — |
Reaction Steps
A 2.0-g (0.024-mol) sample of methoxyamine hydrochloride was added slowly to a slurry of 3.0 g (0.012 mol) beta-(N-chloroacetyl-2,6-dimethylphenylamino)propionaldehyde and 2.0 g (0.02 mol) sodium bicarbonate in 75 ml ethanol. The reaction mixture was stirred at about 35° C. for 2 hours, filtered and evaporated to give 2.9 g of the product as an oil. The product is tabulated in Table I as Compound No. 13-B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04174210 |
|---|
| Source dataset | uspto-grants-1979_11 |
|---|
| ORD ID | ord-54a847b5ccec4255aa8ee077062b0e96 |
|---|
| Source note | uspto-grants-1979_11 |
|---|
