4-(1-Propynyl)iodobenzene → HCID 178439006, compound

Participants

Reaction Steps

Trans-4-propylcyclohexylphenylacetylene (2.3 g, 0.01 mol) and 4-(1-propynyl)iodobenzene (2.4 g, 0.01 mol) were dissolved in diethylamine (20 ml), and then copper iodide (0.11 g, 0.15 mmol) and dichlorobistriphenylphosphinepalladium dichloride (0.21 g, 0.3 mmol) were added. The resulting mixture was subjected to reaction and purification operation in the same manner as in Example 1 to obtain the objective 4-(trans-4-propylcyclohexyl)-4'-(1-propyl)tolan (compound No. 57) (1.8 g). (CS point: 118.9° C., SN point: 127.4° C., NI point: 245.1° C.)

Provenance & Evidence