HCID 17872858, compound → Aspirin

HRID 465900Notes

Reaction equation

HRID 465900 reaction equation
[C:1]([OH:4])(=[O:3])[CH3:2].[C:5]([OH:14])(=[O:13])[C:6]1[C:7](=[CH:9][CH:10]=[CH:11][CH:12]=1)O>C(O)C>[CH3:2][C:1]([O:4][C:12]1[CH:11]=[CH:10][CH:9]=[CH:7][C:6]=1[C:5]([OH:14])=[O:13])=[O:3]

Participants

3

Reactant 1

HCID 17872858HCID 17872858, compound

Product 1

HCID 2244Aspirin

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

Desalted egg phosphatides (Hepar) were dissolved in ethanol at a concentration of 250 mg/ml in a 1000 ml flask. To 400 mg of salicylic acid acetate, 1.6 ml of the above solution containing 400 mg of phosphatides was added and the solution adjusted with absolute ethanol to 4 ml. The final concentration of both ingredients in this pharmacological agent-lipid solution was 100 mg/ml. This procedure was performed at about 22.5° C.+/- about 2.5° C. and atmospheric pressure.

Workup

  1. additionwas added
  2. customwas performed at about 22.5° C.

Sources & evidence

ORD record
ord-9207797ec18c4ee88558d75b9a94b7ad
Source dataset
uspto-grants-1992_10
Patent number
US05154930

Reaction notes

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