Sulfuric Acid → HCID 178441881, compound

HRID 465993Notes

Reaction equation

HRID 465993 reaction equation
[CH3:1][C:2]([CH3:11])([CH3:10])[C:3]([NH:5][NH:6][C:7]([NH2:9])=[O:8])=O.[OH-].[K+].S(=O)(=O)(O)O>>[C:2]([C:3]1[NH:5][NH:6][C:7](=[O:8])[N:9]=1)([CH3:11])([CH3:10])[CH3:1]

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 14797Potassium HydroxideHCID 15671597HCID 15671597, compound

Product 1

HCID 178441881HCID 178441881, compoundYield 45%

Conditions

Temperature
100 °C

Procedure

To the white powder of the trimethylacetyl semicarbazide obtained was added 1500 ml of a 5% aqueous potassium hydroxide solution, and the mixture was heated to 100° C. while stirring. After the contents were completely dissolved, the solution was further heated at 100° C. for one hour, and the reaction mixture then cooled and neutralized by an addition of conc. sulfuric acid. The white precipitates formed were collected by filtration, washed with water, and then dried under a reduced pressure to yield 64 g of white powder of 3-tert-butyl-1H-1,2,4-triazole-5-one. (yield 45%)

Workup

  1. dissolutionAfter the contents were completely dissolved
  2. temperaturethe solution was further heated at 100° C. for one hour
  3. temperaturethe reaction mixture then cooled
  4. customThe white precipitates
  5. customformed
  6. filtrationwere collected by filtration
  7. washwashed with water
  8. customdried under a reduced pressure

Sources & evidence

ORD record
ord-886296dcbba74faba3394dfa42b40b9c
Source dataset
uspto-grants-1992_10
Patent number
US05155124

Reaction notes

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