Aluminium lithium hydride → HCID 23346565, compound

HRID 46607Notes

Reaction equation

HRID 46607 reaction equation
[O:1]1[CH:12]2[C:2]1([CH3:15])[C:3]1([C:9]([CH3:14])([CH3:13])[CH2:10][CH2:11]2)[O:7][CH:6]([CH3:8])[CH:5]=[CH:4]1.[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[CH3:8][CH:6]1[CH:5]=[CH:4][C:3]2([C:9]([CH3:14])([CH3:13])[CH2:10][CH2:11][CH2:12][C:2]2([CH3:15])[OH:1])[O:7]1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 23346563HCID 23346563, compound

Product 1

HCID 23346565HCID 23346565, compoundYield 174.2%

Procedure

1.08 g (0.01 M) of 6,7-epoxy-2,6,10,10-tetramethyl-1-oxa-spiro[4.5]dec-3-ene -- see method B, letter i-- were reduced by means of 570 mg (0.015 M) of LiAlH4 in accordance with the above process. After the usual treatments of washing, drying and evaporation, the fractional distillation of the obtained residue gave 1.9 g (ca. 90%) of 2,6,10,10-tetramethyl-1-oxa-spiro[4.5]dec-3-ene-6-ol, b.p. 80°-90°/0.1 Torr.

Workup

  1. washAfter the usual treatments of washing
  2. customdrying
  3. customevaporation
  4. distillationthe fractional distillation of the obtained residue

Sources & evidence

ORD record
ord-76f6aa5000e54802b468a8a196e25898
Source dataset
uspto-grants-1979_11
Patent number
US04174327

Reaction notes

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