3-Methylbenzoyl chloride → HCID 14049598, compound

HRID 466112Notes

Reaction equation

HRID 466112 reaction equation
[Cl:1][C:2]1[C:3]([OH:9])=[CH:4][C:5](=[O:8])[NH:6][CH:7]=1.[CH3:10][C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][CH:19]=1)[C:14](Cl)=[O:15]>>[Cl:1][C:2]1[C:3]([O:9][C:14](=[O:15])[C:13]2[CH:17]=[CH:18][CH:19]=[C:11]([CH3:10])[CH:12]=2)=[CH:4][C:5]([O:8][C:14](=[O:15])[C:13]2[CH:17]=[CH:18][CH:19]=[C:11]([CH3:10])[CH:12]=2)=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 743753-Methylbenzoyl chlorideHCID 54679224Gimeracil

Product 1

HCID 14049598HCID 14049598, compoundYield 44.3%

Procedure

The general procedure of Example 5 was followed using 2.00 g of 5-chloro-4-hydroxy-2-pyridone and 3.00 g of 3-methylbenzoyl chloride, thereby producing 1.64 g of the title compound in a yield of 32%.

Sources & evidence

ORD record
ord-8ff0bfc3f3c54fe6b416031e4c75c612
Source dataset
uspto-grants-1992_10
Patent number
US05155113

Reaction notes

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