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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 466113Generated: October 29, 2026

Benzoyl chloride → 4-Benzoyloxy-2-pyridone

https://huagongshe.com/reaction/466113

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl chlorideHCID 7412—
Reactant4-Hydroxy-2(1H)-pyridinoneHCID 54696004—
SolventPyridineHCID 1049—
Product4-Benzoyloxy-2-pyridoneHCID 1404966244%

Reaction Steps

50 ml of a solution of 1.00 g of 4-hydroxy-2-pyridone and 1.35 ml of benzoyl chloride in pyridine was refluxed for 6 hours. After the pyridine was distilled off, the residue was mixed with water. The precipitate was recovered by filtration and was washed with a small amount of ethanol to obtain 0.86 g of the title compound in a yield of 44%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05155113
Source datasetuspto-grants-1992_10
ORD IDord-ff2759b4c10a440087bdb0d6c4f019b1
Source noteuspto-grants-1992_10