Benzyl 3-chlorocarbonylbenzoate → 4-(3-Benzyloxycarbonylbenzoyloxy)-2-pyridone

HRID 466115Notes

Reaction equation

HRID 466115 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][NH:5][C:4](=[O:8])[CH:3]=1.[CH2:9]([O:16][C:17]([C:19]1[CH:20]=[C:21]([CH:25]=[CH:26][CH:27]=1)[C:22](Cl)=[O:23])=[O:18])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH2:9]([O:16][C:17]([C:19]1[CH:20]=[C:21]([CH:25]=[CH:26][CH:27]=1)[C:22]([O:1][C:2]1[CH:7]=[CH:6][NH:5][C:4](=[O:8])[CH:3]=1)=[O:23])=[O:18])[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 19815207Benzyl 3-chlorocarbonylbenzoateHCID 546960044-Hydroxy-2(1H)-pyridinone

Product 1

HCID 140496634-(3-Benzyloxycarbonylbenzoyloxy)-2-pyridoneYield 49%

Procedure

The general procedure of Example 1 was repeated using 2.80 g of 4-hydroxy-2-pyridone and 14.70 g of 3-benzyloxycarbonylbenzoyl chloride, thereby producing 4.29 g of the title compound in a yield of 49%.

Sources & evidence

ORD record
ord-cb2922094a564731a4ed5320f3c5aef5
Source dataset
uspto-grants-1992_10
Patent number
US05155113

Reaction notes

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