Propionyl chloride → HCID 14049664, compound

HRID 466117Notes

Reaction equation

[OH:1][C:2]1[CH:7]=[CH:6][NH:5][C:4](=[O:8])[CH:3]=1.[C:9](Cl)(=[O:12])[CH2:10][CH3:11]>>[C:9]([O:1][C:2]1[CH:7]=[CH:6][NH:5][C:4](=[O:8])[CH:3]=1)(=[O:12])[CH2:10][CH3:11]

Participants

Reactant 2

HCID 62324Propionyl chloride

HCID 546960044-Hydroxy-2(1H)-pyridinone

Product 1

HCID 14049664HCID 14049664, compoundYield 23%

Procedure

Using 1.00 g of 4-hydroxy-2-pyridone and 0.94 ml of propanoyl chloride and following the general procedure of Example 12, 350 mg of the title compound was obtained in a yield of 23%.

Sources & evidence

ORD record: ord-c733b13ceacb4270b0b2008699733a29
Source dataset: uspto-grants-1992_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05155113

Reaction notes

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