Benzoyl chloride → HCID 19815229, compound

HRID 466124Notes

Reaction equation

HRID 466124 reaction equation
[C:1]([O:4][C:5]1[C:10]([Cl:11])=[CH:9][NH:8][C:7](=[O:12])[CH:6]=1)(=[O:3])[CH3:2].[C:13](Cl)(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[C:1]([O:4][C:5]1[C:10]([Cl:11])=[CH:9][N:8]=[C:7]([O:12][C:13](=[O:20])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:6]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 7412Benzoyl chlorideHCID 14049647HCID 14049647, compound

Product 1

HCID 19815229HCID 19815229, compoundYield 93%

Procedure

The general procedure of Example 20 was repeated using 500 mg of 4-acetoxy-5-chloro-2-pyridone and 0.37 ml of benzoyl chloride to produce 720 mg of the title compound in a yield of 93%.

Sources & evidence

ORD record
ord-575da1e3c85a43b6b14c623a5dcbd7a1
Source dataset
uspto-grants-1992_10
Patent number
US05155113

Reaction notes

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