4-Methylbenzoyl Chloride → HCID 178425873, compound

HRID 466129Notes

Reaction equation

HRID 466129 reaction equation
C[Si](C)(C)[O:3][C:4]1[CH:9]=[C:8]([O:10][Si](C)(C)C)[CH:7]=[CH:6][N:5]=1.[CH3:17][C:18]1[CH:26]=[CH:25][C:21]([C:22](Cl)=[O:23])=[CH:20][CH:19]=1>C(Cl)Cl>[OH:10][C:8]1[CH:7]=[CH:6][N:5]=[C:4]([O:3][C:22](=[O:23])[C:21]2[CH:25]=[CH:26][C:18]([CH3:17])=[CH:19][CH:20]=2)[CH:9]=1

Participants

4

Reactant 2

HCID 134054-Methylbenzoyl ChlorideHCID 21819823HCID 21819823, compound

Product 1

HCID 178425873HCID 178425873, compoundYield 59.2%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To 3.5 g of 2,4-bis(trimethylsilyloxy)-pyridine in 50 ml of methylene chloride was added 2.34 g of p-methylbenzoyl chloride and the mixture was stirred at room temperature for one hour. Following thereafter the general procedure of Example 27, 1.86 g of the title compound was produced in a yield of 59.2%.

Sources & evidence

ORD record
ord-35af19d4c6574b6398f1bc582fe04995
Source dataset
uspto-grants-1992_10
Patent number
US05155113

Reaction notes

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