Ethyl isocyanate → HCID 54738561, compound

Participants

Reaction Steps

A 2.50 ml quantity of ethyl isocyanate was added to a suspension of 3.00 g of 4-hydroxy-2-pyridone in 20 ml of pyridine, and the mixture was stirred at room temperature for one hour. The solvent was distilled off and the residue was dissolved in 50 ml of ethyl acetate. The solution was washed twice with 30 ml of water. The ethyl acetate layer was dried on anhydrous sodium sulfate and concentrated. The concentrate was recrystallized from ethanol-ether, thereby producing 1.48 g of the title compound in a yield of 30.1%.

Provenance & Evidence