1,3-Benzodioxole-5-carbonyl chloride → HCID 14049602, compound

HRID 466146Notes

Reaction equation

[Cl:1][C:2]1[C:3]([OH:9])=[CH:4][C:5](=[O:8])[NH:6][CH:7]=1.[C:10](Cl)(=[O:20])[C:11]1[CH:19]=[CH:18][C:17]2[O:16][CH2:15][O:14][C:13]=2[CH:12]=1>>[Cl:1][C:2]1[C:3]([O:9][C:10](=[O:20])[C:11]2[CH:19]=[CH:18][C:17]3[O:16][CH2:15][O:14][C:13]=3[CH:12]=2)=[CH:4][C:5]([O:8][C:10](=[O:20])[C:11]2[CH:19]=[CH:18][C:17]3[O:16][CH2:15][O:14][C:13]=3[CH:12]=2)=[N:6][CH:7]=1

Participants

Reactant 2

HCID 27347491,3-Benzodioxole-5-carbonyl chloride

HCID 54679224Gimeracil

Product 1

HCID 14049602HCID 14049602, compoundYield 4%

Procedure

The general procedure of Example 45 was followed using 2.00 g of 5-chloro-4-hydroxy-2-pyridone and 3.80 g of piperonyloyl chloride, thereby producing 180 mg of the title compound in a yield of 3%.

Sources & evidence

ORD record: ord-268d81ede818498e8b6f6c36b29aa001
Source dataset: uspto-grants-1992_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05155113

Reaction notes

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