Chloromethyl Methyl Ether → HCID 54734105, compound

HRID 466155Notes

Reaction equation

HRID 466155 reaction equation
C[Si](C)(C)[O:3][C:4]1[CH:9]=[C:8]([O:10][Si](C)(C)C)[C:7]([Cl:15])=[CH:6][N:5]=1.[CH3:18][O:19][CH2:20]Cl>C(#N)C>[Cl:15][C:7]1[C:8]([OH:10])=[CH:9][C:4](=[O:3])[N:5]([CH2:18][O:19][CH3:20])[CH:6]=1

Participants

4

Reactant 2

HCID 7864Chloromethyl Methyl EtherHCID 14049611HCID 14049611, compound

Product 1

HCID 54734105HCID 54734105, compoundYield 55%

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The general procedure of Example 61 was followed using 1.75 g of 2,4-bis(trimethylsilyloxy)-5-chloropyridine, 0.66 g of chloromethyl methyl ether and 20 ml of acetonitrile, thereby producing 0.63 g of the title compound in a yield of 49%.

Sources & evidence

ORD record
ord-92aef3ded2514299a366627e2987223a
Source dataset
uspto-grants-1992_10
Patent number
US05155113

Reaction notes

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