18-Crown-6 → HCID 178524593, compound

Participants

Reaction Steps

There were mixed 0.15 g of potassium fluoride, 0.35 g of 18-crown-6 and 50 ml of acetonitrile. The mixture was refluxed for 30 minutes and 0.50 g of 5-bromo-2,4-dibenzoyloxypyridine was added thereto. The mixture was refluxed overnight, left to stand for cooling and concentrated. The concentrate was extracted with ethyl acetate and washed with water. The ethyl acetate layer was concentrated and the concentrate was treated with ether, giving 0.23 g of the title compound in a yield of 62%.

Provenance & Evidence