Benzoyl chloride → 3-Cyano-2,6-dibenzoyloxypyridine

HRID 466165Notes

Reaction equation

HRID 466165 reaction equation
[C:1]([O:9][C:10]1[N:15]=[C:14]([OH:16])[C:13]([C:17]#[N:18])=[CH:12][CH:11]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:19](Cl)(=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[C:17]([C:13]1[C:14]([O:16][C:19](=[O:26])[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[N:15][C:10]([O:9][C:1](=[O:8])[C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:11][CH:12]=1)#[N:18]

Participants

3

Reactant 2

HCID 7412Benzoyl chlorideHCID 178510098HCID 178510098, compound

Product 1

HCID 140496413-Cyano-2,6-dibenzoyloxypyridineYield 80.9%

Procedure

The general procedure of Example 90 was followed using 1.00 g of 6-benzoyloxy-3-cyano-2-hydroxypyridine and 0.58 g of benzoyl chloride, thereby producing 1.15 g of the title compound in a yield of 80%.

Sources & evidence

ORD record
ord-216e5842547a4d909979ff8eb2e6704a
Source dataset
uspto-grants-1992_10
Patent number
US05155113

Reaction notes

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