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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 466167Generated: October 29, 2026

3-Methylbenzoyl chloride → 3-Cyano-6-(3-methylbenzoyloxy)-2-hydroxypyridine

https://huagongshe.com/reaction/466167

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methylbenzoyl chlorideHCID 74375—
ReactantHCID 178510101HCID 178510101—
Product3-Cyano-6-(3-methylbenzoyloxy)-2-hydroxypyridineHCID 17842531558%

Reaction Steps

The general procedure of Example 81 was followed using 2.00 g of 3-cyano-2,6-dihydroxypyridine and 2.27 g of 3-methylbenzoyl chloride, thereby producing 2.16 g of the title compound in a yield of 58%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05155113
Source datasetuspto-grants-1992_10
ORD IDord-a9564cf7c9d9482995ee40ba7964fca6
Source noteuspto-grants-1992_10