6-Hydroxybenzo[d][1,3,2]benzodioxaphosphepine 6-oxide → 4-[3-[(2-Hydroxyethyl)[3-(methylsulfinyl)propyl]amino]propoxy]-benzonitrile

HRID 466217Notes

Reaction equation

HRID 466217 reaction equation
[CH2:1]([N:3]([CH2:17][CH2:18][CH2:19][S:20]([CH2:22]CC)=[O:21])[CH2:4][CH:5](O)[CH2:6][O:7][C:8]1[CH:15]=[CH:14][C:11]([C:12]#[N:13])=[CH:10][CH:9]=1)[CH3:2].P1(O)(OC2C=CC=CC=2C2C=CC=CC=2O1)=[O:26]>>[OH:26][CH2:2][CH2:1][N:3]([CH2:17][CH2:18][CH2:19][S:20]([CH3:22])=[O:21])[CH2:4][CH2:5][CH2:6][O:7][C:8]1[CH:15]=[CH:14][C:11]([C:12]#[N:13])=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 6191486-Hydroxybenzo[d][1,3,2]benzodioxaphosphepine 6-oxideHCID 3033962Almokalant

Product 1

HCID 150668564-[3-[(2-Hydroxyethyl)[3-(methylsulfinyl)propyl]amino]propoxy]-benzonitrile

Procedure

4-[3-[ethyl[3-(propylsulfinyl)propyl]amino]-2-hydroxypropoxy]-benzonitrile, addition salt with biphenyl-2,2'-diyl hydrogen phosphate

Sources & evidence

ORD record
ord-0b42e689afa8463999ff764c76bc0e32
Source dataset
uspto-grants-1992_10
Patent number
US05155133

Reaction notes

Loading…