HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N'-Bis(2-aminoethyl)-1,3-propanediamine → 4-(5,7-Dioxo-1,4,8,11-tetraazacyclotetradecan-6-yl)butanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N'-Bis(2-aminoethyl)-1,3-propanediamine | HCID 78479 | — |
| Reactant | 3-(3-Cyanopropyl)-2,4-dioxo-1,5,8,11-tetraazacyclotridecane | HCID 20386763 | — |
| Product | 4-(5,7-Dioxo-1,4,8,11-tetraazacyclotetradecan-6-yl)butanenitrile | HCID 12365201 | 30% |
Reaction Steps
The procedure of (2) of Example 1 was repeated with the exception that N,N'-bis(2-aminoethyl)-1,3-propylenediamine was used in place of triethylenetetramine. Thus, 3-(3-cyanopropyl)-2,4-dioxo-1,5,8,12-tetraaza-cyclotetradecane (C-substituted cyclic diamide) was obtained in a yield of 30%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04174428 |
| Source dataset | uspto-grants-1979_11 |
| ORD ID | ord-550cf5d5cb87479f92c09e9963b1db77 |
| Source note | uspto-grants-1979_11 |