関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 5-Butyramido-2-propylimidazo[4,5-b]pyridine | HCID 22407381 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 5-Amino-2-propylimidazo[4,5-b]pyridine | HCID 22407584 | 79.6% |
反応手順
A mixture of 5-butyramido-2-propylimidazo[4,5-b]pyridine (250 mg, 1.07 mmol), MeOH (20 mL), and concentrated aqueous HCl (2 mL) was heated to 45° C. for 16 hours. Concentration and neutralization with NaHCO3 gave 150 mg of the title compound as a glass.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05157026 |
|---|
| 出典データセット | uspto-grants-1992_10 |
|---|
| ORD ID | ord-741260a1cda0425aa0ade90c6fe251f0 |
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| 出典メモ | uspto-grants-1992_10 |
|---|
