Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | HCID 178437403 | HCID 178437403 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178437454 | HCID 178437454 | 51.9% |
Reaction Steps
A mixture of 5-Bromo-2-ethyl-7-methyl-3-(2'-(tetrazol-5-yl)biphen-4-yl)methyl-3H-imidazo[4,5-b]pyridine (74 mg), methylamine (0.6 g), and EtOH (2 mL) was heated in a bomb at 180° C. for 16 hours. Concentration and purification (SiO2, 90/9/1 CH2Cl2 /MeOH/NH4OH) gave 34.4 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05157026 |
|---|
| Source dataset | uspto-grants-1992_10 |
|---|
| ORD ID | ord-58dc009491594d0ba9e956f59daa6453 |
|---|
| Source note | uspto-grants-1992_10 |
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