Pyridine → HCID 53978061, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of dry pyridine (0.45 mL) in methylene chloride (30 mL) cooled to -15° C. is added trifluoromethanesulfonic anhydride (0.84 mL). The mixture is stirred during 15 min at -10° C., then methyl 2,3,6-tri-O-benzyl-4-deoxy-4-hydroxymethyl-α-D-glucopyranoside (1.19 g, 2.49 mmol) in methylene chloride (5 mL) is added. The mixture is stirred during 1.5 h at -10° C. The reaction mixture is washed with water. The organic layer is dried over sodium sulfate, filtered and concentrated under reduced pressure so as to afford an oil which is the expected triflate methyl 2,3,6-tri-O-benzyl-4-deoxy-4-trifluoromethylsulfonyloxymethyl-α-D-glucopyranoside.

Provenance & Evidence