Ammonia → HCID 19813246, compound

HRID 466978Notes

Reaction equation

HRID 466978 reaction equation
[S:1]1[CH:5]=[CH:4][S:3][C:2]1=[C:6]([C:13]([O:15]C(OCC)=O)=O)[C:7]([O:9][CH:10]([CH3:12])[CH3:11])=[O:8].[NH3:21]>C(#N)C>[S:1]1[CH:5]=[CH:4][S:3][C:2]1=[C:6]([C:13](=[O:15])[NH2:21])[C:7]([O:9][CH:10]([CH3:12])[CH3:11])=[O:8]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 19813261HCID 19813261, compound

Product 1

HCID 19813246HCID 19813246, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Isopropyl 2-(1,3-dithiol-2-ylidene)-2-(ethoxycarbonyloxy-carbonyl)acetate (20.65 g) was added to a solution of ammonia in acetonitrile (150 ml) and the mixture was stirred at room temperature for an hour. The reaction mixture was evaporated to dryness and the residue was recrystallized from methylene chloride to obtain the pure product. (12.0 g, 77%)

Workup

  1. customThe reaction mixture was evaporated to dryness
  2. customthe residue was recrystallized from methylene chloride
  3. customto obtain the pure product

Sources & evidence

ORD record
ord-59a1084c854b44dda9128fa20c57fba7
Source dataset
uspto-grants-1992_10
Patent number
US05158950

Reaction notes

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