N-Methylaniline → HCID 19813254, compound

Participants

Reaction Steps

Isopropyl 2-(1,3-dithiol-2-ylidene)-2-(ethoxycarbonyloxy-carbonyl)acetate (15.9 g) and N-methylaniline (6.43 g) were dissolved in methylene chloride (100 ml). The solution was stirred at room temperature for 24 hrs. The resultant mixture was washed with aqueous sodium hydroxide solution, dil-HCl and water. After removal of solvent the residue was purified by column chromatography on silica gel using petroleum ether/ethyl acetate (9:1) as an eluent to give the product (13.2 g, 78.7%) as a yellow oil.

Provenance & Evidence