反应详情

0.135 mole=44 g of 7-benzyloxy-1-(2,5-dithiapentyl)-heptane-3-one were heated for 1 hour under nitrogen and under reflux in 1 liter of acetone with [0.275 mole]=47 g of CuCl2 . 2 H2O and [0.57 mole]=44 g of CuO, the copper salts were filtered off and the filtrate was concentrated under reduced pressure. The residue was dissolved in ether, washed twice with 2N- HCl and thrice with water, dried and the solvent was removed by distillation under reduced pressure. The residue was distilled under reduced pressure. B.p.0.5 mm 185°-192° C.

1. filtration2 H2O and [0.57 mole]=44 g of CuO, the copper salts were filtered off
2. concentrationthe filtrate was concentrated under reduced pressure
3. dissolutionThe residue was dissolved in ether
4. washwashed twice with 2N- HCl and thrice with water
5. customdried
6. customthe solvent was removed by distillation under reduced pressure
7. distillationThe residue was distilled under reduced pressure
8. customB.p.0.5 mm 185°-192° C.