HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Ethyl-N-(6-nitroquinol-2-ylmethyl)-4-methanesulphonamidophenethylamine → N-ethyl-N-(6-aminoquinol-2-ylmethyl)-4-methanesulphonamidophenethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Ethyl-N-(6-nitroquinol-2-ylmethyl)-4-methanesulphonamidophenethylamine | HCID 19813443 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | N-ethyl-N-(6-aminoquinol-2-ylmethyl)-4-methanesulphonamidophenethylamine | HCID 19813422 | 99.7% |
Reaction Steps
The product of part (A) (0.55 g) was catalytically hydrogenated similarly to Preparation 1(C) but using H2 over 5% Pd on C in ethyl acetate at 15 p.s.i. (103.4 kPa) for 3 hours, giving the title compound (0.51 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05158964 |
| Source dataset | uspto-grants-1992_10 |
| ORD ID | ord-a04bb7abd80543c690206d67e82d49a7 |
| Source note | uspto-grants-1992_10 |