Ammonia → HCID 19813651, compound

HRID 467228Notes

Reaction equation

HRID 467228 reaction equation
Cl[C:2]([N:4]([C:13]1[N:18]=[C:17]([CH3:19])[CH:16]=[C:15]([CH3:20])[N:14]=1)[C:5]1[CH:10]=[C:9]([Cl:11])[CH:8]=[CH:7][C:6]=1[Cl:12])=[O:3].[NH3:21]>C(Cl)(Cl)Cl>[Cl:12][C:6]1[CH:7]=[CH:8][C:9]([Cl:11])=[CH:10][C:5]=1[N:4]([C:13]1[N:18]=[C:17]([CH3:19])[CH:16]=[C:15]([CH3:20])[N:14]=1)[C:2]([NH2:21])=[O:3]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 19813658HCID 19813658, compound

Product 1

HCID 19813651HCID 19813651, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

4.0 g (0.012 mole) of N-chlorocarbonyl-N-(4,6-dimethylpyrimidin-2-yl)-2,5-dichloroaniline are dissolved in 50 ml of chloroform. An excess of ammonia gas is introduced into the solution. When the exothermic reaction has subsided, the reaction mixture is washed twice with water, dried with magnesium sulfate and concentrated by evaporation.

Workup

  1. customWhen the exothermic reaction
  2. washthe reaction mixture is washed twice with water
  3. dry with materialdried with magnesium sulfate
  4. concentrationconcentrated by evaporation

Sources & evidence

ORD record
ord-defa99a31dca4aa6af3a7ae31432c945
Source dataset
uspto-grants-1992_10
Patent number
US05159078

Reaction notes

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