HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isovaleric Acid → HCID 178501453, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isovaleric Acid | HCID 10430 | — |
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | HCID 178501501 | HCID 178501501 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 178501453 | HCID 178501453 | — |
Reaction Steps
A 2.0 g (8.9 mMol) portion of arginine methyl ester hydrochloride was contacted with isovaleric acid (755 mg), HOBT (1 g), triethylamine (747 mg) and DCC (1.52 g) in DMF (150 ml) under the conditions described in Example 30 to give N-isovaleryl-arginine methyl ester as a crystalline solid (1.71 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05159081 |
| Source dataset | uspto-grants-1992_10 |
| ORD ID | ord-77fb880fb6484d6c97be4af81875ee0a |
| Source note | uspto-grants-1992_10 |