Leucine, N-carboxy-, N-benzyl ester, L- → HCID 88127025, compound

HRID 467305Notes

Reaction equation

HRID 467305 reaction equation
[Br:1][CH2:2][C:3]([CH2:5][Br:6])=[O:4].[CH2:7]([O:14][C:15]([NH:17][C@H:18]([C:23]([OH:25])=O)[CH2:19][CH:20]([CH3:22])[CH3:21])=[O:16])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.C(OC([NH:36][C@H:37]([C:42]([OH:44])=[O:43])[CH2:38]C(C)C)=O)C1C=CC=CC=1>>[Br:1][CH2:2][C:3]([CH2:5][Br:6])=[O:4].[CH2:7]([O:14][C:15]([NH:17][C@H:18]([C:23]([NH:36][C@H:37]([C:42]([OH:44])=[O:43])[CH3:38])=[O:25])[CH2:19][C:20]1[CH:21]=[CH:5][CH:3]=[CH:2][CH:22]=1)=[O:16])[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 74840Leucine, N-carboxy-, N-benzyl ester, L-HCID 88127293HCID 88127293, compound

Product 1

HCID 88127025HCID 88127025, compound

Procedure

N-Benzyloxycarbonyl-L-leucine bromomethyl ketone (an oil) from N-benzyloxycarbonyl-L-leucine.

Sources & evidence

ORD record
ord-bff456088d8446659dd82c1ffcb3a8f0
Source dataset
uspto-grants-1992_10
Patent number
US05158936

Reaction notes

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