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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 467359Generated: October 26, 2026

Dicyclohexylcarbodiimide → HCID 178427520, compound

https://huagongshe.com/reaction/467359

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDicyclohexylcarbodiimideHCID 10868—
Reactant3a,4,7,7a-Tetrahydro-2-hydroxy-4,7-methano-1H-isoindole-1,3(2H)-dioneHCID 89529—
ReactantL-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-HCID 90234—
ReactantHCID 178427521HCID 178427521—
ProductHCID 178427520HCID 178427520—

Reaction Steps

Using 3.90 g Boc-Phe-D-Arg(Tos)-Tyr(Bzl)-OBzl, 1.60 g Boc-Ser(Bzl)-OH, 1.08 g HONB and 1.24 g DCC, the desired product was obtained in exactly the same manner as in Example 1-(III).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05159061
Source datasetuspto-grants-1992_10
ORD IDord-179f9939a8654510ae0a5e3300089ff6
Source noteuspto-grants-1992_10