Tert-butyl (piperidin-4-ylmethyl)carbamate → Nitrobenzene

HRID 467549Notes

Reaction equation

HRID 467549 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5](F)=[C:4]([N+:9]([O-:11])=[O:10])[CH:3]=1.N1CCC(CNC(=O)OC(C)(C)C)CC1>>[N+:9]([C:4]1[CH:5]=[CH:6][CH:7]=[CH:2][CH:3]=1)([O-:11])=[O:10]

Participants

3

Reactant 2

HCID 723429Tert-butyl (piperidin-4-ylmethyl)carbamateHCID 27363284-Bromo-1-fluoro-2-nitrobenzene

Product 1

HCID 7416Nitrobenzene

Procedure

Nitrobenzene Int-15b was prepared by following similar procedures to those described in Step A of Example 2 using 4-bromo-1-fluoro-2-nitrobenzene and tert-butyl piperidin-4-ylmethylcarbamate as starting materials.

Sources & evidence

ORD record
ord-b08829ceb50041ef8b3d09826c8dfd90
Source dataset
uspto-grants-2014_01
Patent number
US08623857B2

Reaction notes

Loading…