1-Methyl-4-nitro-1H-pyrazole-3-carboxylic acid → N,1-dimethyl-4-nitropyrazole-3-carboxamide

HRID 467635Notes

Reaction equation

HRID 467635 reaction equation
[CH3:1][N:2]1[CH:6]=[C:5]([N+:7]([O-:9])=[O:8])[C:4]([C:10]([OH:12])=O)=[N:3]1.Cl.[CH3:14][NH2:15]>>[CH3:14][NH:15][C:10]([C:4]1[C:5]([N+:7]([O-:9])=[O:8])=[CH:6][N:2]([CH3:1])[N:3]=1)=[O:12]

Participants

3

Reactant 2

HCID 5359761-Methyl-4-nitro-1H-pyrazole-3-carboxylic acidHCID 6364545Methylamine hydrochloride

Product 1

HCID 1256475N,1-dimethyl-4-nitropyrazole-3-carboxamide

Procedure

The product was obtained according to the method described in example 1, step 1 starting from 1-methyl-4-nitro-1H-pyrazole-3-carboxylic acid and methylamine hydrochloride as light yellow solid (250 mg, 64%).

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-5f9aa406c1f44004bf676640643ebf37
Source dataset
uspto-grants-2014_01
Patent number
US08623866B2

Reaction notes

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