Ammonium Chloride → 1-Methyl-4-nitro-1H-pyrazole-3-carboxamide

HRID 467637Notes

Reaction equation

HRID 467637 reaction equation
[CH3:1][N:2]1[CH:6]=[C:5]([N+:7]([O-:9])=[O:8])[C:4]([C:10]([OH:12])=O)=[N:3]1.[Cl-].[NH4+:14]>>[CH3:1][N:2]1[CH:6]=[C:5]([N+:7]([O-:9])=[O:8])[C:4]([C:10]([NH2:14])=[O:12])=[N:3]1

Participants

3

Reactant 2

HCID 25517Ammonium ChlorideHCID 5359761-Methyl-4-nitro-1H-pyrazole-3-carboxylic acid

Product 1

HCID 12555571-Methyl-4-nitro-1H-pyrazole-3-carboxamide

Procedure

The product was obtained according to the method described in example 1, step 1 starting from 1-methyl-4-nitro-1H-pyrazole-3-carboxylic acid and two equivalents of ammonium chloride as amine source as light yellow solid (110 mg, 37%).

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-bf9c17c59c834af988fb241cdbb12ba1
Source dataset
uspto-grants-2014_01
Patent number
US08623866B2

Reaction notes

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