Bromomethylcyclopropane → HCID 70114948, compound

Participants

Reaction Steps

The product was obtained according to the method described in example 4, step 2 starting from 4-nitro-1H-pyrazole-3-carboxylic acid ethyl ester and bromomethyl-cyclopropane as a mixture of regioisomers which were separated by silica gel chromatography using a heptane/ethyl acetate gradient to yield 88 mg (23%) of the desired regioisomer and 179 mg (46%) of 1-cyclopropylmethyl-4-nitro-1H-pyrazole-3-carboxylic acid ethyl ester.

Provenance & Evidence