HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-1,2-propanediol → HCID 58548392, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-1,2-propanediol | HCID 73561 | — |
| Reactant | 4-{[6-Cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester | HCID 70099200 | — |
| Product | HCID 58548392 | HCID 58548392 | 15% |
Reaction Steps
According to the general method described in step 5 of example 27, reaction of 3-amino-propane-1,2-diol with 4-{[6-cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester provided the title compound (15%) as sticky solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08623866B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-f372da8e5ac04e4c967297f80f6f3555 |
| Source note | uspto-grants-2014_01 |