HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazin-2-one → HCID 58548351, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazin-2-one | HCID 231360 | — |
| Reactant | 4-{[6-Cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester | HCID 70099200 | — |
| Product | HCID 58548351 | HCID 58548351 | 12% |
Reaction Steps
According to the general method described in step 5 of example 27, reaction of piperazine-2-one with 4-{[6-cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester provided the title compound (12%) as pale yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08623866B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-d7a0fadbdf9f45ae8c2ce939291ab43a |
| Source note | uspto-grants-2014_01 |