HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-1,2-propanediol → HCID 70098408, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-1,2-propanediol | HCID 73561 | — |
| Reactant | 3-{[6-Cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-isonicotinic acid | HCID 70098054 | — |
| Product | HCID 70098408 | HCID 70098408 | 33% |
Reaction Steps
According to the general method described in step 3 of example 53, reaction of 3-amino-propan-1,2-diol with 3-{[6-cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-isonicotinic acid provided the title compound (33%) as amorphous yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08623866B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-e6797766fe9746ce9dda8045e6631ae1 |
| Source note | uspto-grants-2014_01 |