Methylamine hydrochloride → HCID 70117432, compound

HRID 467711Notes

Reaction equation

HRID 467711 reaction equation
C(O[C:4]([C:6]1[C:7]([NH2:21])=[CH:8][C:9]2[N:10]([CH:12]=[C:13]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[N:14]=2)[CH:11]=1)=[O:5])C.Cl.[CH3:23][NH2:24]>>[CH3:23][NH:24][C:4]([C:6]1[C:7]([NH2:21])=[CH:8][C:9]2[N:10]([CH:12]=[C:13]([C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=3)[N:14]=2)[CH:11]=1)=[O:5]

Participants

3

Reactant 2

HCID 6364545Methylamine hydrochlorideHCID 70115249HCID 70115249, compound

Product 1

HCID 70117432HCID 70117432, compoundYield 60%

Procedure

According to the procedure described in step 1 of example 18 7-amino-2-phenyl-imidazo[1,2-a]pyridine-6-carboxylic acid ethyl ester was reacted with methylamine hydrochloride to give the title compound as off-white solid (60%).

Sources & evidence

ORD record
ord-5172fab8d73340b1a55c3dde8a9fd855
Source dataset
uspto-grants-2014_01
Patent number
US08623866B2

Reaction notes

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