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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 467733Generated: October 25, 2026

3-Methoxy-2,2-dimethylpropan-1-amine hydrochloride → HCID 58548267, compound

https://huagongshe.com/reaction/467733

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methoxy-2,2-dimethylpropan-1-amine hydrochlorideHCID 46782157—
Reactant3-{[6-Cyclopropyl-3-(pyrimidin-5-ylamino)-pyrazine-2-carbonyl]-amino}-isonicotinic acidHCID 70098928—
ProductHCID 58548267HCID 5854826754%

Reaction Steps

According to the procedure described in step 3 of example 99, 3-{[6-cyclopropyl-3-(pyrimidin-5-ylamino)-pyrazine-2-carbonyl]-amino}-isonicotinic acid (example 99, step 2) was reacted with 3-methoxy-2,2-dimethylpropan-1-amine hydrochloride, the title compound as yellow solid (54%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08623866B2
Source datasetuspto-grants-2014_01
ORD IDord-f3a1684ca14344f1ba0805ddb71b29c9
Source noteuspto-grants-2014_01