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HRID467775

反应详情

EQUATION

反应方程式

HRID 467775 的结构方程式

REACTANTS

反应物

2
结构：NC[C@@H]1CCCO1
HCID641530

(S)-(+)-Tetrahydrofurfurylamine

C5H11NO

结构：Cn1ncc(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)c1C(=O)O
HCID70098073

未命名化合物

PRODUCTS

生成物

1
结构：Cn1ncc(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)c1C(=O)NC[C@@H]1CCCO1
HCID54759456

未命名化合物

PROCEDURE

实验过程

The product was obtained starting from 4-{[6-cyclopropyl-3-(pyrimidin-5-ylamino)-pyrazine-2-carbonyl]-amino}-2-methyl-2H-pyrazole-3-carboxylic acid (30 mg, 79 μmol; example 236, step 3) and (S)-(tetrahydrofuran-2-yl)methanamine (15 μl, 142 μmol) according to the method described in example 64, step 6 after purification by preparative HPLC using an acetonitrile/water gradient as yellow solid (31 mg, 84%).

WORKUP

后处理

  1. customThe product was obtained
  2. customafter purification by preparative HPLC