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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 467804Generated: October 27, 2026

(1S,2R)-2-Aminocyclopentane-1-carboxylic acid → rel-(1R,2S)-2-Amino-N-(1-methylethyl)cyclopentanecarboxamide

https://huagongshe.com/reaction/467804

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1S,2R)-2-Aminocyclopentane-1-carboxylic acidHCID 73306—
ReactantCyclopentanecarboxylic acid, 2-amino-HCID 429614—
Productrel-(1R,2S)-2-Amino-N-(1-methylethyl)cyclopentanecarboxamideHCID 24896496—

Reaction Steps

The chiral compound (1S,2R)-2-aminocyclopentane-carboxylic acid isopropylamide is prepared analogously to this procedure using (1S,2R)-2-aminocyclopentanecarboxylic acid. In addition, a number of amides are prepared in this way starting from 2-aminocyclopentanecarboxylic acid (racemic or chiral).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08623887B2
Source datasetuspto-grants-2014_01
ORD IDord-08b49b5347d64940ad9234f627bae746
Source noteuspto-grants-2014_01