HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 2,6-Dimethyl-6-piperidino-4-hepten-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 2-Methyl-3-buten-2-ol | HCID 8257 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 1-Bromo-2-methyl-1-propene | HCID 98560 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Product | 2,6-Dimethyl-6-piperidino-4-hepten-2-ol | HCID 54023182 | 31% |
Reaction Steps
A mixture of 10 mmoles 2-methyl-1-bromo-1-propene, 12.5 mmoles 2-methyl-3-buten-2-ol, 30 mmoles piperidine, 0.20 mmole palladium acetate and 0.40 mmole triphenylphosphine was reacted at 100° C. There was produced 61% of a mixture of nonadienols, 31% 2,6-dimethyl-6-piperidino-4-hepten-2-ol and 6% of what is believed to be 2,6-dimethyl-4-piperidino-5-hepten-2-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04175187 |
| Source dataset | uspto-grants-1979_11 |
| ORD ID | ord-2a8da2881cb74fe29c07cbad6f53654a |
| Source note | uspto-grants-1979_11 |