反应详情

A mixture of 76.5 g. of α-hydroxy-N-methyl-α-phenyl-o-toluamide and (0.314 mole) 150 ml. o-dichlorobenzene is heated at reflux for 18 hours. The mixture is cooled and filtered and the resulting solid triturated with cold ether to give 3-phenyl phthalide.

1. additionA mixture of 76.5 g
2. temperatureat reflux for 18 hours
3. temperatureThe mixture is cooled
4. filtrationfiltered
5. customthe resulting solid triturated with cold ether