反应详情

A mixture of 55.2 g. of 3-phenyl phthalide (0.263 mole), 600 ml. ethanol and 5.9 g. of 10% Pd/C is hydrogenated at room temperature and 50 psi until 1 equivalent of H2 is absorbed. The catalyst is removed by filtration and the solvent removed in vacuo and the residue triturated in petroleum ether to give α-phenyl-o-toluic acid; m.p. 101°-104° C.

1. additionA mixture of 55.2 g
2. customis hydrogenated at room temperature
3. custom50 psi until 1 equivalent of H2 is absorbed
4. customThe catalyst is removed by filtration
5. customthe solvent removed in vacuo
6. customthe residue triturated in petroleum ether